Selection criteria and scientific validation for True Age biomarkers
True Age is built on four specific biomarkers: VO2max, resting heart rate, heart rate variability, and lean body mass index. Here's why we selected these four and not others.
Every biomarker in True Age must meet three critical criteria:
Each biomarker has been validated in peer-reviewed longitudinal studies as a predictor of all-cause mortality. These aren't trendy metrics. They're established health indicators with decades of research behind them.
You can track all four biomarkers using widely available wearables and apps. No lab visits or expensive tests required.
You can improve all four biomarkers through exercise, sleep, nutrition, and stress management. True Age isn't a genetic lottery. It's a reflection of your habits.
No single biomarker tells the whole story. True Age combines all four to give you a complete picture of your cardiovascular and metabolic health.
Someone with excellent VO2max but poor HRV might be overtraining. Someone with low resting heart rate but declining muscle mass might be losing functional capacity. True Age captures these nuances.
As wearable technology advances, we'll add more biomarkers that meet our criteria:
Metabolic markers (glucose, HbA1c, lipids)
Inflammatory markers (CRP)
Sleep architecture
Blood pressure
Cognitive performance
For now, we're focused on the four biomarkers that are most proven, most measurable, and most actionable.
